| Andrew William Oliver |
205,882,352,941 |
£226,470,588 |
| TD Direct Investing Nominees |
94,495,144,706 |
£103,944,659 |
| HSDL Nominees Limited |
81,968,497,647 |
£90,165,347 |
| David Lenigas |
79,411,764,706 |
£87,352,941 |
| Greenhair Services Limited |
73,235,294,118 |
£80,558,824 |
| Academy Minerals Limited |
70,588,235,294 |
£77,647,059 |
| Kavi Dhana |
44,021,067,059 |
£48,423,174 |
| IP2IPO Limited (together with Techtran Group Limited) |
34,418,058,824 |
£37,859,865 |
| XCAP Nominees Limited |
19,824,847,059 |
£21,807,332 |
| IP Venture Fund Limited |
16,302,105,882 |
£17,932,316 |
| Mr Mark V Houghton-Berry |
12,335,376,471 |
£13,568,914 |
| The University of Leeds |
9,552,264,706 |
£10,507,491 |
| The Wellcome Trust Limited |
6,107,858,824 |
£6,718,645 |
| Adrian Stiff |
37,000,000 |
£40,700 |
| Hargreaves Lansdown |
27,752,212 |
£30,527 |
| JIM Nominees Limited |
27,116,707 |
£29,828 |
| Pershing Nominees |
26,006,789 |
£28,608 |
| Hargreaves Lansdown (Nominees) Limited Des 15942 |
25,609,943 |
£28,171 |
| Chris Akers |
25,000,000 |
£27,500 |
| Vidacos Nominees Limited |
20,709,150 |
£22,780 |
| The Bank OF New York (Nominees) Limited Des 672938 |
19,705,371 |
£21,676 |
| Oberon Investments |
19,705,371 |
£21,676 |
| Barclays Direct Investing Nominees Limited |
19,358,393 |
£21,294 |
| Winterflood Securities Limited |
18,278,266 |
£20,106 |
| Donald Strang |
17,820,211 |
£19,602 |
| Interactive Investor Services Nominees Limited |
17,219,649 |
£18,942 |
| ABN Amro Bank |
13,801,956 |
£15,182 |
| Hargreaves Lansdown (Nominees) Limited Des VRA |
12,572,701 |
£13,830 |
| David Graham Brown |
12,100,000 |
£13,310 |
| Sebastian Marr |
8,180,672 |
£8,999 |