| Vulpes Life Sciences Fund |
618,542,844 |
£1,141,212 |
| Pentwater Capital Management LP |
500,000,000 |
£922,500 |
| Unicorn Asset Management Limited |
278,464,859 |
£513,768 |
| Sankofa Strategic Equity Fund Limited |
211,855,049 |
£390,873 |
| Trafalgar Capital Management (HK) Limited |
130,316,163 |
£240,433 |
| Arbuthnot Latham (Nominees) Limited |
74,250,303 |
£136,992 |
| William Henry Salomon |
60,000,000 |
£110,700 |
| Odey Funds |
26,945,092 |
£49,714 |
| Lombard Odier Asset Management (Europe) Limited |
15,568,816 |
£28,724 |
| Dr Yavuz Ahiska |
10,577,600 |
£19,516 |
| Seneca Partners Limited |
9,978,822 |
£18,411 |
| Armistice Capital LLC |
7,791,803 |
£14,376 |
| Investec Wealth & Investment Limited |
7,319,886 |
£13,505 |
| The Chancellor, Masters and Scholars of the University of Oxford |
5,724,476 |
£10,562 |
| GL Healthcare Investment L.P. |
4,688,000 |
£8,649 |
| PHILIPPA MARGARET HOYER MILLAR |
4,473,140 |
£8,253 |
| The Goldman Sachs Group, Inc. |
4,404,088 |
£8,126 |