Portfolio

Half-year Financial Report

By Sharecast

Date: Wednesday 31 Dec 2025







RNS Number : 2879N
Provexis PLC
31 December 2025
 



31 December 2025


 


Provexis plc


 


UNAUDITED INTERIM RESULTS FOR SIX MONTHS TO 30 SEPTEMBER 2025


 


Provexis plc ("Provexis" or the "Company"), the business that develops, licenses and sells the proprietary, scientifically-proven Fruitflow® heart-health functional food ingredient, announces its unaudited interim results for the six months ended 30 September 2025.


 


Highlights


 


·      Total revenue for the period £364k (six months ended 30 September 2024: £785k), including £302k from Fruitflow II SD (2024: £725k) and £62k (2024: £60k) from Fruitflow+ Omega-3.


 


·      On 29 October 2025 the Company announced in its full year results statement that all of the remaining Fruitflow II SD inventory which the Company purchased from DSM in 2023 and 2024 had been sold. A new production run of Fruitflow II SD was completed in October 2025, two months later than envisaged / booked, and this delay from a third party led to temporarily lower sales in August and September 2025, prior to the new material being delivered.


 


·      The Company has taken orders for and / or has sold several hundred thousand pounds of Fruitflow II SD in the current period after 30 September 2025, and it is dealing with numerous sales enquiries from existing and new customers for further direct sales of Fruitflow in 2026 and beyond.


 


·      In this favourable context the Company is now planning with its outsourced supply chain partners to undertake at least three further production runs of Fruitflow II SD in the next twelve months, the first of which is currently expected to be delivered in February 2026.


 


·      The planned launch by BYHEALTH, a circa £2bn listed Chinese dietary supplement business, of a number of Fruitflow based products in the Chinese market has been progressing well, with potential sales volumes remaining at a significant multiple of existing Fruitflow sales.


 


·      BYHEALTH continues to work on an extensive regulatory submission to the Chinese SAMR, seeking to establish a new permitted health function claim for foods such as Fruitflow that can demonstrate an anti-platelet effect. BYHEALTH has stated publicly that it has invested 'tens of millions of funds' (RMB) in the research and development work. The Company and BYHEALTH entered into a supply and distribution agreement for Fruitflow in 2021 and the parties remain in close and constructive dialogue, at a high level. The Company will provide shareholders with as much information as it can on the timing of this commercially sensitive and potentially transformative project, subject to the multi-party confidentiality arrangements which surround the process.


 


·      The Company's long term commercial partnership with dsm-firmenich ('DSM') has progressed well during the period, with continuing interest from some significant global customers. The commercial partnership is based on: (i) a Premix and Market-Ready Solutions supply agreement for Fruitflow II SD; and (ii) the use of Fruitflow to confer health benefits in modulating the gut microbiome of humans.


 


·      Underlying operating loss* for the period of £155k (six months ended 30 September 2024: £98k).


 


*Loss from operations, adjusted for non-cash share-based payments of £155k (2024: £49k).


 


Provexis CEO Ian Ford commented:


'The Company is pleased to report on another strong period of progress.


 


The Company's long term commercial partnership with dsm-firmenich ('DSM') has progressed well during the period, with continuing interest from some significant global customers. The commercial partnership is based on: (i) a Premix and Market-Ready Solutions supply agreement for Fruitflow II SD; and (ii) the use of Fruitflow to confer health benefits in modulating the gut microbiome of humans.


 


Provexis has been working with BYHEALTH for more than nine years to support the planned launch of a number of Fruitflow based products in the Chinese market. In August 2023 the Company was delighted to report that BYHEALTH had submitted: i) the first application for a new permitted health function claim and ii) some related product registration applications. BYHEALTH has noted that it has been working on the project since 2015, with 'tens of millions of funds' (RMB) invested by BYHEALTH in the research and development work. The Company will provide shareholders with as much information as it can on the timing of this commercially sensitive and potentially transformative project, subject to the multi-party confidentiality arrangements which surround the process.


 


The Company has developed a strong, long lasting and wide-ranging patent portfolio for Fruitflow, and it owns outright four existing patent families for Fruitflow. The new microbiome patent application takes this to a potential total of five patent families, with potential patent protection now running out to 2042. The four existing patent families have a truly global footprint, and the Company also holds other valuable intellectual property and trade secrets for Fruitflow. The intellectual property for Fruitflow is of fundamental importance to the Company and its current and future commercial partners, to include DSM and BYHEALTH, and it underpins the numerous commercial opportunities which the Company and its partners are pursuing for Fruitflow.


 


On 29 October 2025 the Company announced in its full year results statement that all of the remaining Fruitflow II SD inventory which the Company purchased from DSM in 2023 and 2024 had been sold. A new production run of Fruitflow II SD was completed in October 2025, two months later than envisaged / booked, and this delay from a third party led to temporarily lower sales in August and September 2025, prior to the new material being delivered.


 


The Company has taken orders for and / or has sold several hundred thousand pounds of Fruitflow II SD in the current period after 30 September 2025, and it is dealing with numerous sales enquiries from existing and new customers for further direct sales of Fruitflow in 2026 and beyond.


 


In this favourable context the Company is now planning with its outsourced supply chain partners to undertake at least three further production runs of Fruitflow II SD in the next twelve months, the first of which is currently expected to be delivered in February 2026.


 


The Company expects that (i) the significant changes to the sales and supply chain structure for Fruitflow from January 2023, (ii) the gut microbiome patent application and related long-term partnership with DSM and (iii) the recent BYHEALTH regulatory developments in China will have a strongly beneficial effect on the current and future commercial prospects for Fruitflow and the business worldwide. The Company would like to thank its customers and shareholders for their continued support, and the Board remains strongly positive about the outlook for Fruitflow and the Provexis business for the coming year and beyond.'


 


 


For further information please contact:


 














Provexis plc


Ian Ford, CEO


Dawson Buck, Non-executive Chairman


 



Tel:         07490 391888


              enquiries@provexis.com



Allenby Capital Limited (Nominated Adviser and Broker)


Nick Naylor / Ashur Joseph


 



Tel:         020 3328 5656


 







 


Chairman and CEO's statement


The Company has had an active and successful first six months of the year, and it has made further progress with the commercial prospects of its innovative, patented Fruitflow® heart-health ingredient.


 


DSM Nutritional Products - new agreements for Fruitflow®


Provexis entered into a long-term Alliance Agreement with DSM Nutritional Products ('DSM'), which is part of DSM-Firmenich AG, in 2010 to commercialise Fruitflow through sales as an ingredient to brand owners in the food, beverage and dietary supplement categories, with a contractual term for the Alliance Agreement which ran to 31 December 2022.


 


More than 100 regional consumer healthcare brands have now been launched by direct customers of DSM, and a number of further regional brands have been launched through DSM's distributor channels. An increasing number of commercial projects have been initiated by DSM with prospective customers in recent years, including some prospective customers which are part of global businesses, and the total projected annual sales value of the prospective sales pipeline for Fruitflow, which is now shared across Provexis and DSM, continues to stand at a substantial multiple of existing annual sales.


 


In June 2022 Provexis announced it had secured two new agreements with DSM for Fruitflow, to replace the Alliance Agreement: (i) a Transfer of Business agreement; and (ii) a Premix and Market-Ready Solutions supply agreement, which both took effect on 1 January 2023.


 


The Company also announced the filing of a new patent application in June 2022 relating to the use of Fruitflow to confer health benefits in modulating the gut microbiome of humans. This followed the completion of a successful human study, the results of which strongly support the use of Fruitflow for modulating gut microbiota to confer a number of health benefits, to include a reduction in TMAO (trimethylamine-n-oxide).


 


Under the terms of the two new agreements with DSM, and the June 2022 patent application:


 


·      DSM's existing and prospective customers for Fruitflow as a straight ingredient (not a Premix or Market-Ready solution) transferred to become direct customers of Provexis from 1 January 2023, and the Company took over the wholly outsourced supply chain / production process for Fruitflow from DSM at that time.


 


·      A royalty is payable to DSM on the gross profits generated from Fruitflow sales to customers transferred from DSM over the first four years of the Transfer of Business agreement. The six months ended 30 September 2025 was covered under the lower third year rate to 31 March 2025; the royalty will decrease further, and at a higher rate of year-on-year decrease, from 1 January 2026, and it will wholly cease to be payable on 31 December 2026.


 


·      A new partnership was agreed with DSM in 2022 relating to the gut microbiome patent, giving DSM preferential access to the use, marketing, and sale of Fruitflow based products which are based on the patent, subject to certain milestones which have been agreed between the parties. DSM conducted a strong launch of the new microbiome technology (www.dsm.com/human-nutrition/en/talking-nutrition/press-releases/2023-01-20-new-study-reveals-dsms-fruitflow-activates-gut-heart.html), with widespread trade press coverage. The technology has seen strong and ongoing interest from some significant global customers.


 


·      Provexis is selling Fruitflow as a straight ingredient to DSM exclusively for use in DSM's Premix Solutions and Market-Ready Solutions businesses, with DSM then looking to sell the resulting Premix and Market-Ready Solutions products on to its customers. The Company looks forward to supporting DSM and its Premix and Market-Ready Solutions customers for many years to come.


 


From 1 January 2023 the Group's sales channels for Fruitflow therefore include:


 


1.   Former DSM customers for Fruitflow;


2.   DSM and its Premix and Market-Ready Solutions businesses, which will leverage the resources and relationships of DSM in some of the major global markets, and seek to commercialise the gut microbiome patent;


3.   New customers for Fruitflow as a straight ingredient;


4.   BYHEALTH and its customers, through the Company's long-term supply and distribution agreement for Fruitflow with BYHEALTH; and


5.   The Group's Fruitflow+ Omega-3 dietary supplement product which is sold direct to consumers, the Group will also look to serve its Chinese Cross-Border e-commerce ('CBEC') distributor for this product in China.


 


On 29 October 2025 the Company announced in its full year results statement that all of the remaining Fruitflow II SD inventory which the Company purchased from DSM in 2023 and 2024 had been sold. A new production run of Fruitflow II SD was completed in October 2025, two months later than envisaged / booked, and this delay from a third party led to lower sales in August and September 2025, prior to the new material being delivered.


 


The Company has taken orders for and / or has sold several hundred thousand pounds of Fruitflow II SD in the current period after 30 September 2025, and it is dealing with numerous sales enquiries from existing and new customers for further direct sales of Fruitflow in 2026 and beyond.


 


In this favourable context the Company is now planning with its outsourced supply chain partners to undertake at least three further production runs of Fruitflow II SD in the next twelve months, the first of which is currently expected to be delivered in February 2026.


 


BYHEALTH Co., Ltd.


In November 2021 the Company announced it had entered into a supply and distribution agreement (the 'BYHEALTH Agreement') for Fruitflow with BYHEALTH, a listed Chinese dietary supplement business with a market capitalisation of approximately £2 billion.


 


The BYHEALTH Agreement, which followed the Company's extensive work with BYHEALTH over the last nine years, took full effect from 1 January 2023 and it gives BYHEALTH exclusive supply and distribution rights to commercialise Fruitflow in Mainland China, Hong Kong, Macau, Taiwan and Australia (the 'Territories').


 


Under the BYHEALTH Agreement Provexis is responsible for the manufacture, supply and sale of Fruitflow to BYHEALTH, and BYHEALTH is responsible for the manufacture, marketing and sale of Fruitflow based functional food and dietary supplement finished products in the Territories, through BYHEALTH's extensive sales network. BYHEALTH also has exclusive rights to act as the distributor of Fruitflow as an ingredient in the Territories.


 


Provexis and BYHEALTH will seek to collaborate on research and development projects which may result in the development and approval of Fruitflow as a drug, for potential sale and distribution in the Territories.


 


The Company and BYHEALTH remain in close and constructive dialogue, at a high level, to include joint consideration of the opportunities to file further patents in China and elsewhere for Fruitflow.


 


Regulatory progress in China - new permitted health function claim


Provexis has been working with BYHEALTH for more than nine years to support the planned launch of a number of Fruitflow based products in the Chinese market. Clinical studies conducted in China are typically required to obtain the necessary regulatory clearances in China, and a significant investment in eight separate Fruitflow studies has been undertaken at BYHEALTH's expense. Completed studies have shown excellent results in use for Fruitflow, and they provide strong evidence for the efficacy of Fruitflow on platelet function.


 


The Chinese regulatory system for functional health food ingredients, such as Fruitflow, is governed by the State Administration for Market Regulation (the 'SAMR') and it is based on a defined list of permitted health function claims which brand owners are permitted to use on product labels.


 


The SAMR provides the possibility of adding new health function claims to the list, with claims needing to demonstrate a relationship between a food or nutrient and a consequent health improvement, subject to evaluation and verification by the SAMR.


 


SAMR certified functional health foods are required to use a blue cap / blue hat logo on their product packaging, which identifies products as approved functional health foods in China.


 


BYHEALTH has been working on an extensive regulatory submission to the SAMR seeking to establish a new permitted health function claim for foods such as Fruitflow that can demonstrate an anti-platelet effect, inhibiting platelet function and conferring beneficial health effects.


 


On 28 August 2023 the SAMR announced in China that the 'Implementation Rules for Health Food New Functions and Product Technology Evaluation' (the 'Implementation Rules') had been agreed by the SAMR in June 2023, and these new rules took effect from 28 August 2023.


 


On 29 August 2023 it was announced in China that BYHEALTH had submitted: i) the first application under the Implementation Rules, seeking to obtain a new permitted health function claim for foods such as Fruitflow which help to 'maintain normal platelet aggregation function and benefit blood flow health'; and ii) some related product registration applications.


 


The significance of these major developments for Fruitflow in China is further outlined here www.nutraingredients-asia.com/Article/2023/09/05/china-set-to-approve-new-function-claims-for-health-foods#. BYHEALTH has noted that it has been working on the project since 2015, with 'tens of millions of funds' (RMB) invested by BYHEALTH in the research and development work.


 


The Company has previously stated that if BYHEALTH is successful in obtaining a new permitted health function claim in China for functional health foods, such as Fruitflow, that can demonstrate an anti-platelet effect, it is expected that this would result in some significant orders for Fruitflow, potentially at a multiple of current total sales values.


 


The Company will provide shareholders with as much information as it can on the timing of this commercially sensitive and potentially transformative process, subject to the multi-party confidentiality arrangements which surround the matter.


 


Fruitflow+ dietary supplement products


Fruitflow+ Omega-3 is available to purchase from the Company's subscription focussed e-commerce website www.fruitflowplus.com, and from Amazon UK.


 


The Fruitflow+ Omega-3 business reported sales in the period of £62k (2024: £61k), reflecting largely unchanged subscriber numbers on the www.fruitflowplus.com website.


 


Fruitflow+ Omega-3 has a social media presence on Facebook www.facebook.com/FruitflowPlus, Instagram www.instagram.com/fruitflowplus and Twitter / X https://twitter.com/FruitflowPlus.


 


The Company is seeking to expand further its commercial activities with Fruitflow+ Omega-3 and other Fruitflow+ combination products, and it is currently in dialogue with some other potential international direct selling customers.


 


 


Intellectual property


The Company is responsible for filing and maintaining patents and trade marks for Fruitflow, and patent coverage for Fruitflow now includes the following patent families which are all owned outright by Provexis:


 
































Patent family


 



Developments in the period from Sep-25 to Dec-25



Improved Fruitflow / Fruit Extracts


Improved Fruitflow / Fruit Extracts, with patents granted by the European Patent Office in January 2017, September 2020, April 2023 and July 2025.


 


Patents have been granted in twelve other major territories to include China and USA; and applications are at a late stage of progression in a further two global territories, with potential patent protection out to November 2029.


 



 


Patents have been validated before national patent offices of seven European states and a Hong Kong patent allowed.


 


 


 



Antihypertensive (blood pressure lowering) effects


This patent was originally developed in collaboration with the University of Oslo, and it has now been granted for Fruitflow in Europe, the US and four other territories. A patent application is being progressed in Japan, with potential patent protection out to April 2033.


 


In August 2020 the Company announced it had agreed to purchase the background and joint foreground blood pressure lowering IP owned by Inven2 AS, the technology transfer office at the University of Oslo, and Provexis now owns these important patents outright, with the licensing option originally held by Inven2 having been cancelled.


 



 


A patent application is pending in Japan.


 



Fruitflow with nitrates in mitigating exercise-induced inflammation and for promoting recovery from intense exercise


Patents have been granted around Europe and in the US, Australia, Brazil, Canada, China, Hong Kong, India, Israel, Japan, South Korea, the Philippines, New Zealand and Mexico. A second patent has been allowed in Europe.


 


Further patent protection is being sought in the USA and Hong Kong, with potential patent protection out to December 2033.


 



 


 


 


A patent has been allowed in Europe and grant formalities are being addressed before the European Patent Office.


 


 


 



Fruitflow for air pollution


The use of Fruitflow in protecting against the adverse effects of air pollution on the body's cardiovascular system.


 


Laboratory work has shown that Fruitflow can reduce the platelet activation caused by airborne particulate matter, such as that from diesel emissions, by approximately one third.


 


US, Australian, Brazilian, Indonesian, Israeli, Japanese Malaysian, Mexican, New Zealand and Taiwanese patents have been secured and there are pending applications in seven jurisdictions (including the US where a further application has been filed) which extends potential patent protection for Fruitflow out to November 2037.


 



 


Patent protection has been allowed in New Zealand.


 



Fruitflow to confer health benefits in modulating the gut microbiome of humans


The Company filed a patent application in June 2022 relating to the use of Fruitflow to confer health benefits in modulating the gut microbiome of humans. This followed the completion of a successful human study, the results of which strongly support the use of Fruitflow for modulating gut microbiota to confer a number of health benefits.


 


Following the completion of the international patent procedure, applications have been filed in 16 jurisdictions (including China, Europe and the USA) with potential patent protection out to June 2043.


 



 


 


Patent applications have been filed in Australia, Brazil, Canada, China, Europe, Hong Kong, India, Indonesia, Israel, Japan, South Korea, Malaysia, Mexico, New Zealand, the Philippines and the USA.



 


 


Capital structure and funding


The Company is seeking to maximise the commercial returns that can be achieved from its Fruitflow technology, and the Company's cost base and its resources continue to be very tightly managed. The Company remains keen to minimise dilution to shareholders and it is focussed on moving into profitability as Fruitflow revenues increase, but while the Company remains in a loss-making position it may need to raise funds in the future to meets its working capital requirements.


 


Under the terms of the DSM Transfer of Business agreement which was announced in June 2022, DSM's existing and prospective customers for Fruitflow II SD as a straight ingredient (not a DSM Premix or DSM Market-Ready solution) transferred to become direct customers of Provexis from 1 January 2023.


 


The Company has needed to hold Fruitflow II SD in stock from 1 January 2023 onwards to sell to new and existing customers, and it was agreed with DSM in 2022 that the Company would have the option to purchase some but not necessarily all of DSM's remaining stocks of Fruitflow at 31 December 2022.


 


In the year ended 31 March 2025 the Company purchased the remainder of DSM's 2022 stocks of Fruitflow in the form of two equity settled transactions which were completed on 5 April 2024 and 24 December 2024. Inventory with a fair value in excess of £623,000 was acquired as part of these two share issues, and the Company has sold all of the inventory which it acquired from DSM.


 


In December 2024 Provexis and DSM also agreed that the estimated royalty for the two years ended 31 December 2024 would be settled in equity, which it duly was as part of the 24 December 2024 share issue. The Company will owe DSM further royalties for the two years ended 31 December 2026, and the Company will seek and has forecast in its sensitivity analysis / scenario planning to settle these royalties in equity as well.


 


The share issues to DSM have been of direct benefit to the Company's cash resources and net assets, and they have helped the Company to fund a new production run of Fruitflow II SD which has recently been completed by the Company's outsourced supply chain partners for Fruitflow.


 


The Company received delivery of the new batch of Fruitflow II SD in October 2025, two months later than originally envisaged, and it has paid its outsourced supply chain partners for this new inventory, in cash.


 


The Company is dealing with numerous sales enquiries from existing and new customers for further direct sales of Fruitflow in 2026 and beyond, in which favourable context the Company is now planning with its outsourced supply chain partners to undertake at least three further production runs of Fruitflow II SD in the next twelve months. The magnitude and timing of these production runs will be determined with reference to (i) estimated customer demand over the subsequent 12 to 18 months, (ii) the comparative costs and timing of a potential production run for a new batch of material and (iii) the Company's financial resources at that time.


 


The new production runs are likely to require a significant cash outlay, as the Company is seeking by necessity to hold greater stocks of Fruitflow to keep up with increasing demand for the product.


 


The Company is in ongoing dialogue with its existing and prospective customers for Fruitflow II SD, seeking their assistance as best possible with forecast volume estimates. A considerable degree of uncertainty is inherent in the forecasting process, which is subject to existing and new customers' changing plans, requirements and regulatory progress, and inevitably there is a wide range of possible outcomes in terms of overall forecast demand.


 


The production process for Fruitflow II SD takes place in two stages, which need to be booked with its outsourced supply chain partners well in advance of production taking place. The Company is in close dialogue with all key parties in its supply chain for Fruitflow, to include: (i) maximum capacity planning; (ii) production cost and other efficiencies; and (iii) the potential requirement for much larger batches of Fruitflow II SD to be made at relatively short notice.


 


With regards to sensitivity analysis, management have prepared scenario planning to stress-test potential impacts on the cash position of the business, which have included (i) different revenue outcomes, (ii) interruption of trade, (iii) no sales growth, (iv) customer failure, and (v) the possible need to pay the remaining royalties due to DSM for the two years ended 31 December 2026 in cash and not shares. In each of these downside stress tests there are a number of mitigating actions that could be taken.


 


In the coming months, based on its current level of cash, the Group may therefore need to raise further equity finance or potentially new loan finance, subject in large part to (i) the size / volume of new production runs of Fruitflow II SD which the Company may need to commission, with larger production runs inevitably requiring more cash at the outset, (ii) the different revenue outcomes which may materialise and (iii) negotiations with DSM, which have yet to be concluded, regarding the royalty payments for the remaining royalty bearing period to 31 December 2026, which the Company will seek to pay in shares and not cash. These three inherently uncertain forecasting issues are together deemed to represent a material uncertainty related to going concern.


 


Considering the success of previous fundraisings and the current performance of the business, the Directors have a reasonable expectation of raising sufficient additional equity capital or new loan finance to continue in operational existence for the foreseeable future. The Company is also engaged in ongoing negotiations with a third party, potentially seeking to hold some of its future stock requirements on a consignment basis, only paying for the stock when it was required for sale.


 


For these reasons the Directors are of the opinion that at 31 December 2025, the Group and Company's liquidity and capital resources are adequate to deliver the current strategic objectives and 2026 business plan and that the Group and Company remain a going concern.


 


Outlook


The Company is pleased to report on another strong period of progress.


 


The Company's long term commercial partnership with dsm-firmenich ('DSM') has progressed well during the period, with continuing interest from some significant global customers. The commercial partnership is based on: (i) a Premix and Market-Ready Solutions supply agreement for Fruitflow II SD; and (ii) the use of Fruitflow to confer health benefits in modulating the gut microbiome of humans.


 


Provexis has been working with BYHEALTH for more than nine years to support the planned launch of a number of Fruitflow based products in the Chinese market. In August 2023 the Company was delighted to report that BYHEALTH had submitted: i) the first application for a new permitted health function claim and ii) some related product registration applications. BYHEALTH has noted that it has been working on the project since 2015, with 'tens of millions of funds' (RMB) invested by BYHEALTH in the research and development work. The Company will provide shareholders with as much information as it can on the timing of this commercially sensitive and potentially transformative project, subject to the multi-party confidentiality arrangements which surround the process.


 


The Company has developed a strong, long lasting and wide-ranging patent portfolio for Fruitflow, and it owns outright four existing patent families for Fruitflow. The new microbiome patent application takes this to a potential total of five patent families, with potential patent protection now running out to 2042. The four existing patent families have a truly global footprint, and the Company also holds other valuable intellectual property and trade secrets for Fruitflow. The intellectual property for Fruitflow is of fundamental importance to the Company and its current and future commercial partners, to include DSM and BYHEALTH, and it underpins the numerous commercial opportunities which the Company and its partners are pursuing for Fruitflow.


 


On 29 October 2025 the Company announced in its full year results statement that all of the remaining Fruitflow II SD inventory which the Company purchased from DSM in 2023 and 2024 had been sold. A new production run of Fruitflow II SD was completed in October 2025, two months later than envisaged / booked, and this delay from a third party led to temporarily lower sales in August and September 2025, prior to the new material being delivered.


 


The Company has taken orders for and / or has sold several hundred thousand pounds of Fruitflow II SD in the current period after 30 September 2025, and it is dealing with numerous sales enquiries from existing and new customers for further direct sales of Fruitflow in 2026 and beyond.


 


In this favourable context the Company is now planning with its outsourced supply chain partners to undertake at least three further production runs of Fruitflow II SD in the next twelve months, the first of which is currently expected to be delivered in February 2026.


 


The Company expects that (i) the significant changes to the sales and supply chain structure for Fruitflow from January 2023, (ii) the gut microbiome patent application and related long-term partnership with DSM and (iii) the recent BYHEALTH regulatory developments in China will have a strongly beneficial effect on the current and future commercial prospects for Fruitflow and the business worldwide. The Company would like to thank its customers and shareholders for their continued support, and the Board remains strongly positive about the outlook for Fruitflow and the Provexis business for the coming year and beyond.


 


Ian Ford                                            Dawson Buck


CEO                                                  Chairman


 






 


































































































































































































































































Consolidated statement of comprehensive income






Unaudited



Unaudited



Audited



Six months ended 30 September 2025






six months



six months



year



 






ended



ended



ended



 






30 September



30 September



31 March



 






2025



2024



2025



 






£



£



£






Notes



 















 















 









Revenue






364,369



785,348



1,292,244



Cost of goods






(194,991)



(512,000)



(759,304)



Gross profit






169,378



273,348



532,940









 









Selling and distribution costs






(40,298)



(32,811)



(68,338)



Research, patent and trade mark costs






(108,041)



(123,716)



(325,625)



Administrative costs - share based payment charges






(154,716)



(49,207)



(168,317)



Administrative costs - other






(176,053)



(215,153)



(422,631)



Loss from operations






(309,730)



(147,539)



(451,971)









 









Finance income






2,584



890



2,334



Loss before taxation






(307,146)



(146,649)



(449,637)









 









Taxation






(3,083)



(12,500)



(3,083)









 









Loss and total comprehensive loss for the period






(310,229)



(159,149)



(452,720)









 















 















 









Attributable to:






 









Owners of the parent






(310,229)



(159,149)



(452,720)



Loss and total comprehensive loss for the period






(310,229)



(159,149)



(452,720)









 















 









Loss per share to owners of the parent






 









Basic and diluted - pence



3



(0.01)



(0.01)



(0.02)









 









 


 






 









































































































































































































































































Consolidated statement of financial position






Unaudited



Unaudited



Audited



30 September 2025






30 September



30 September



31 March









2025



2024



2025









£



£



£









 















 









Assets






 









Current assets






 









Inventories






43,969



152,755



202,352



Trade and other receivables






255,142



144,760



82,202



Corporation tax asset






19,380



46,680



19,380



Cash and cash equivalents






523,348



478,199



708,087



Total current assets






841,839



822,394



1,012,021









 









Total assets






841,839



822,394



1,012,021









 









Liabilities






 









Current liabilities






 









Trade and other payables






(218,914)



(471,006)



(239,621)



Current tax liabilities






(12,037)



-



(8,585)



Total current liabilities






(230,951)



(471,006)



(248,206)









 









Total liabilities






(230,951)



(471,006)



(248,206)









 









Total net assets






610,888



351,388



763,815









 















 









Capital and reserves attributable to






 









owners of the parent company






 









Share capital






2,345,891



2,262,945



2,345,891



Share premium reserve






19,432,882



18,928,940



19,432,882



Foreign exchange reserve






2,586



-



-



Merger reserve






6,599,174



6,599,174



6,599,174



Retained earnings






(27,235,896)



(26,905,922)



(27,080,383)









1,144,637



885,137



1,297,564



Non-controlling interest






(533,749)



(533,749)



(533,749)



Total equity






610,888



351,388



763,815



 


 


 


 






 


















































































































































































































Consolidated statement of cash flows



Unaudited



Unaudited



Audited



30 September 2025



six months



six months



year



 



ended



ended



ended



 



30 September



30 September



31 March



 



2025



2024



2025



 



£



£



£






 












 












 









Cash flows from operating activities



 









Loss after tax



(310,229)



(159,149)



(452,720)



Adjustments for:



 









Finance income



(2,584)



(890)



(2,334)



Taxation



3,452



12,500



3,083



Share-based payment charge - share options



154,716



49,207



168,317



Changes in inventories



160,969



(16,235)



(65,832)



Changes in trade and other receivables



(173,145)



(19,281)



43,682



Changes in trade and other payables



(20,707)



163,558



(67,827)



Net cash flow from operations



(187,528)



29,710



(373,631)






 









Taxation



-



(12,500)



32,802



Total cash flow from operating activities



(187,528)



17,210



(340,829)






 









Cash flow from investing activities



 









Interest received



2,789



890



1,929



Total cash flow from investing activities



2,789



890



1,929






 









Cash flow from financing activities



 









Proceeds from issue of share capital - purchase of inventory



-



270,742



857,630



Total cash flow from financing activities



-



270,742



857,630






 









Net change in cash and cash equivalents



(184,739)



288,842



518,730



Opening cash and cash equivalents



708,087



189,357



189,357



Closing cash and cash equivalents



523,348



478,199



708,087



 






 




























































































































































































































































































































































































Consolidated statement of changes in equity



Share



Share



Foreign



Merger



Retained



Total equity



Non-



Total



30 September 2025



capital



premium



exchange


reserve



reserve



earnings



attributable to owners of



 controlling interests



equity



 


















the parent



 




































£



£



£



£



£



£



£



£

























































At 31 March 2024



2,217,822



18,703,321



-



6,599,174



(26,795,980)



724,337



(533,749)



190,588






























Share-based charges - share options



-



-



-



-



49,207



49,207



-



49,207






























Issue of shares - inventory purchased



45,123



225,619



-



-



-



270,742



-



270,742






























Total comprehensive


expense for the period



-



-



-



-



(159,149)



(159,149)



-



(159,149)






























At 30 September 2024



2,262,945



18,928,940



-



6,599,174



(26,905,922)



885,137



(533,749)



351,388






























Share-based charges - share options



-



-



-



-



119,110



119,110



-



119,110






























Issue of shares - inventory purchased



82,946



503,942



-



-



-



586,888



-



586,888






























Total comprehensive


expense for the period



-



-



-



-



(293,571)



(293,571)



-



(293,571)






























At 31 March 2025



2,345,891



19,432,882



-



6,599,174



(27,080,383)



1,297,564



(533,749)



763,815






























Share-based charges - share options



-



-



-



-



154,716



154,716



-



154,716






























Foreign exchange reserve



-



-



2,586



-



-



2,586



-



2,586






























Total comprehensive


expense for the period



-



-



-



-



(310,229)



(310,229)



-



(310,229)






























At 30 September 2025



2,345,891



19,432,882



2,586



6,599,174



(27,235,896)



1,144,637



(533,749)



610,888

























































 


 






 


1. General information, basis of preparation and accounting policies


 


General information


Provexis plc is a public limited company incorporated and domiciled in the United Kingdom (registration number 05102907). The address of the registered office is 2 Blagrave Street, Reading, Berkshire RG1 1AZ, UK.


 


The main activities of the Group are those of developing, licensing and selling the proprietary, scientifically-proven Fruitflow® heart-health functional food ingredient.


 


Basis of preparation


This condensed financial information has been prepared using accounting policies consistent with International Financial Reporting Standards in the European Union (IFRS).


 


The same accounting policies, presentation and methods of computation are followed in this condensed financial information as are applied in the Group's latest annual audited financial statements, except as set out below. While the financial figures included in this half-yearly report have been computed in accordance with IFRS applicable to interim periods, this half-yearly report does not contain sufficient information to constitute an interim financial report as that term is defined in IAS 34.


 


Use of non-GAAP profit measure - underlying operating profit


The directors believe that the operating loss before share based payments measure provides additional useful information for shareholders on underlying trends and performance. This measure is used for internal performance analysis. Underlying operating loss is not defined by IFRS and therefore may not be directly comparable with other companies' adjusted profit measures. It is not intended to be a substitute for, or superior to IFRS measurements of profit.


 


The interim financial information does not constitute statutory accounts as defined in section 434 of the Companies Act 2006 and has been neither audited nor reviewed by the Company's auditors RPG Crouch Chapman LLP pursuant to guidance issued by the Auditing Practices Board.


 


The results for the year ended 31 March 2025 are not statutory accounts. The statutory accounts for the last year ended 31 March 2025 were approved by the Board on 29 October 2025 and are filed at Companies House. The report of the auditors on those accounts was unqualified, contained an emphasis of matter with respect to going concern, and did not contain a statement under section 498 of the Companies Act 2006.


 


The interim report for the six months ended 30 September 2025 can be downloaded from the Company's website www.provexis.com. Further copies of the interim report and copies of the 2025 annual report and accounts can be obtained by writing to the Company Secretary, Provexis plc, 2 Blagrave Street, Reading, Berkshire RG1 1AZ, UK.


 


This announcement was approved by the Board of Provexis plc for release on 31 December 2025.


 


Going concern


Under the terms of the DSM Transfer of Business agreement which was announced in June 2022, DSM's existing and prospective customers for Fruitflow II SD as a straight ingredient (not a DSM Premix or DSM Market-Ready solution) transferred to become direct customers of Provexis from 1 January 2023.


 


The Company has needed to hold Fruitflow II SD in stock from 1 January 2023 onwards to sell to new and existing customers, and it was agreed with DSM in 2022 that the Company would have the option to purchase some but not necessarily all of DSM's remaining stocks of Fruitflow at 31 December 2022.


 


In the year ended 31 March 2025 the Company purchased the remainder of DSM's 2022 stocks of Fruitflow in the form of two equity settled transactions which were completed on 5 April 2024 and 24 December 2024. Inventory with a fair value in excess of £623,000 was acquired as part of these two share issues, and the Company has sold all of the inventory which it acquired from DSM.


 


In December 2024 Provexis and DSM also agreed that the estimated royalty for the two years ended 31 December 2024 would be settled in equity, which it duly was as part of the 24 December 2024 share issue. The Company will owe DSM further royalties for the two years ended 31 December 2026, and the Company will seek and has forecast in its sensitivity analysis / scenario planning to settle these royalties in equity as well.


 


The share issues to DSM have been of direct benefit to the Company's cash resources and net assets, and they have helped the Company to fund a new production run of Fruitflow II SD which has recently been completed by the Company's outsourced supply chain partners for Fruitflow.


 


The Company received delivery of the new batch of Fruitflow II SD in October 2025, two months later than originally envisaged, and it has paid its outsourced supply chain partners for this new inventory, in cash.


 


The Company is dealing with numerous sales enquiries from existing and new customers for further direct sales of Fruitflow in 2026 and beyond, in which favourable context the Company is now planning with its outsourced supply chain partners to undertake at least three further production runs of Fruitflow II SD in the next twelve months. The magnitude and timing of these production runs will be determined with reference to (i) estimated customer demand over the subsequent 12 to 18 months, (ii) the comparative costs and timing of a potential production run for a new batch of material and (iii) the Company's financial resources at that time.


 


The new production runs are likely to require a significant cash outlay, as the Company is seeking by necessity to hold greater stocks of Fruitflow to keep up with increasing demand for the product.


 


The Company is in ongoing dialogue with its existing and prospective customers for Fruitflow II SD, seeking their assistance as best possible with forecast volume estimates. A considerable degree of uncertainty is inherent in the forecasting process, which is subject to existing and new customers' changing plans, requirements and regulatory progress, and inevitably there is a wide range of possible outcomes in terms of overall forecast demand.


 


The production process for Fruitflow II SD takes place in two stages, which need to be booked with its outsourced supply chain partners well in advance of production taking place. The Company is in close dialogue with all key parties in its supply chain for Fruitflow, to include: (i) maximum capacity planning; (ii) production cost and other efficiencies; and (iii) the potential requirement for much larger batches of Fruitflow II SD to be made at relatively short notice.


 


With regards to sensitivity analysis, management have prepared scenario planning to stress-test potential impacts on the cash position of the business, which have included (i) different revenue outcomes, (ii) interruption of trade, (iii) no sales growth, (iv) customer failure, and (v) the possible need to pay the remaining royalties due to DSM for the two years ended 31 December 2026 in cash and not shares. In each of these downside stress tests there are a number of mitigating actions that could be taken.


 


In the coming months, based on its current level of cash, the Group may therefore need to raise further equity finance or potentially new loan finance, subject in large part to (i) the size / volume of new production runs of Fruitflow II SD which the Company may need to commission, with larger production runs inevitably requiring more cash at the outset, (ii) the different revenue outcomes which may materialise and (iii) negotiations with DSM, which have yet to be concluded, regarding the royalty payments for the remaining royalty bearing period to 31 December 2026, which the Company will seek to pay in shares and not cash. These three inherently uncertain forecasting issues are together deemed to represent a material uncertainty related to going concern.


 


Considering the success of previous fundraisings and the current performance of the business, the Directors have a reasonable expectation of raising sufficient additional equity capital or new loan finance to continue in operational existence for the foreseeable future. The Company is also engaged in ongoing negotiations with a third party, potentially seeking to hold some of its future stock requirements on a consignment basis, only paying for the stock when it was required for sale.


 


For these reasons the Directors are of the opinion that at 31 December 2025, the Group and Company's liquidity and capital resources are adequate to deliver the current strategic objectives and 2026 business plan and that the Group and Company remain a going concern.


 


Accounting policies


The accounting policies applied are consistent with those of the annual financial statements for the year ended 31 March 2025, as described in those annual financial statements.


 






 


2. Segmental reporting


The Group's operating segments are determined based on the Group's internal reporting to the Chief Operating Decision Maker (CODM). The CODM has been determined to be the Board of Directors as it is primarily responsible for the allocation of resources to segments and the assessment of performance of the segments. The performance of operating segments is assessed on revenue.


 


The CODM uses revenue as the key measure of the segments' results as it reflects the segments' underlying trading performance for the financial period under evaluation. Revenue is reported separately to the CODM and all other reports are prepared as a single business unit.


 








































































Revenue



Unaudited



Unaudited



Audited






six months



six months



year






ended



ended



ended






30 September



30 September



31 March






2025



2024



2025






£



£



£






 












 









Fruitflow II SD ingredient



302,183



724,817



1,170,939



Fruitflow+ Omega-3



62,186



60,531



121,305






364,369



785,348



1,292,244



 


 


3. Earnings per share


Basic earnings per share amounts are calculated by dividing the profit attributable to owners of the parent by the weighted average number of ordinary shares in issue during the period.


 


The loss attributable to equity holders of the Company for the purpose of calculating the fully diluted loss per share is identical to that used for calculating the basic loss per share. The exercise of share options or warrants would have the effect of reducing the loss per share and is therefore anti-dilutive under the terms of IAS 33 'Earnings per Share'.


 


Basic and diluted loss per share amounts are in respect of all activities.


 


There were 288,230,000 share options and warrants in issue at 30 September 2025 (2024: 178,500,000) that are currently anti-dilutive and have therefore been excluded from the calculations of the diluted loss per share.


 























































































Unaudited



Unaudited



Audited






six months



six months



year






ended



ended



ended






30 September



30 September



31 March






2025



2024



2025






 












 












 









Loss for the period attributable


to owners of the parent - £



310,229



159,149



452,720






 









Weighted average number of shares



2,345,891,239



2,261,712,366



2,284,370,301






 









Basic and diluted loss per share - pence



0.01



0.01



0.02



 


 


4. Share capital and Total Voting Rights


At 31 December 2025, the date of this announcement, the Company's issued share capital comprises 2,345,891,239 ordinary shares of 0.1 pence each, each with equal voting rights. The Company does not hold any shares in treasury and therefore the total number of ordinary shares and voting rights in the Company is 2,345,891,239.


 


The above figure may be used by shareholders in the Company as the denominator for the calculations by which they will determine if they are required to notify their interest in, or change to their interest in, the share capital of the Company under the FCA's Disclosure Guidance and Transparency Rules.


 


 






 


5. Cautionary statement


This document contains certain forward-looking statements with respect to the financial condition, results and operations of the business. These statements involve risk and uncertainty as they relate to events and depend on circumstances that will incur in the future. Nothing in this interim report should be construed as a profit forecast.


 






This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

RNS may use your IP address to confirm compliance with the terms and conditions, to analyse how you engage with the information contained in this communication, and to share such analysis on an anonymised basis with others as part of our commercial services. For further information about how RNS and the London Stock Exchange use the personal data you provide us, please see our Privacy Policy.
 
END
 
 
IR WPGQGPUPAURG

..

Email this article to a friend

or share it with one of these popular networks:


Top of Page